Publications

A platform for target prediction of phenotypic screening hit molecules

Homeyer N, van Deursen R, Ochoa-Montaño B, Heikamp K, Ray P, Zuccotto F, Blundell T, Gilbert I. J Mol Graph..

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Genetic ablation of purine salvage in Cryptosporidium parvum reveals nucleotide uptake from the host cell

Mattie C. Pawlowic, Mastanbabu Somepalli, Adam Sateriale, Gillian T. Herbert, Alexis R. Gibson, Gregory D. Cuny, Lizbeth Hedstrom, and Boris..

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Proteome turnover in the bloodstream and procyclic forms of Trypanosoma brucei measured by quantitative proteomics

Tinti, M, Güther, MLS, Crozier, TWM, Lamond, AI, Ferguson, MAJ Wellcome Open Res. 2019;4(152)  [version 1; peer review: 3 approved]..

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Trypanosoma cruzi phosphomannomutase and guanosine diphosphate-mannose pyrophosphorylase ligandability assessment

Filip Zmuda, Sharon M. Shepherd, Michael A. J. Ferguson, David. W. Gray, Leah S. Torrie, Manu De Rycker Antimicrob Agents..

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A post-transcriptional respiratome regulon in trypanosomes

Anna Trenaman, Lucy Glover, Sebastian Hutchinson and David Horn Nucleic Acids Res. 2019 Jul 26; 47(13): 7063–7077. Published online 2019..

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Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex.

Joana Faria, Lucy Glover, Sebastian Hutchinson, Cordula Boehm, Mark C. Field, David Horn. Nat Commun [Internet]. 2019;10(1):3023. Abstract The largest..

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Burkholderia pseudomallei D‐alanine‐D‐alanine ligase; detailed characterisation and assessment of a potential antibiotic drug target

Díaz-Sáez L, Torrie LS, McElroy SP, Gray D, Hunter WN FEBS J [Internet]. 2019;286(22):4509–24 Abstract Burkholderia pseudomallei is a serious, difficult to..

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Substituted aminoacetamides as novel leads for malaria

Neil R. Norcross, Caroline Wilson, Beatriz Baragaña, Irene Hallyburton, Maria Osuna-Cabello, Suzanne Norval, Jennifer Riley, Daniel Fletcher, Robert Sinden, Michael..

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Profiling of Antileishmanial Efficacy and Resistance in the Related Kinetoplastid Parasite Trypanosoma brucei .

Collett CF, Kitson C, Baker N, Steele-Stallard HB, Santrot M-V, Hutchinson S, Horn D, Alsford S. Antimicrob Agents Chemother [Internet]...

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Identification of inhibitors of an unconventional Trypanosoma brucei kinetochore kinase

Leah S. Torrie, Fabio Zuccotto, David A. Robinson, David W. Gray, Ian H. Gilbert , Manu De Rycker PLoS ONE..

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