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Publications

Genetic Transformation of Candida auris via Homology-Directed Repair Using a Standard Lithium Acetate Protocol

Gustavo Bravo Ruiz & Alexander Lorenz Methods in Molecular Biology, vol 2517. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2417-3_8   Abstract Reverse..

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High-Throughput Screening Platform To Identify Inhibitors of Protein Synthesis with Potential for the Treatment of Malaria

Fabio Tamaki, Fabio Fisher, Rachel Milne, Fernando Sánchez Román Terán, Natalie Wiedemar, Karolina Wrobel, Darren Edwards, Hella Baumann, Ian H...

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Control of Variant Surface Glycoprotein Expression by CFB2 in Trypanosoma brucei and Quantitative Proteomic Connections to Translation and Cytokinesis

Gustavo Bravo Ruiz , Michele Tinti , Melanie Ridgway, David Horn ASM Journals, mSphere, Vol. 7, No. 2, e00069-22  DOI:..

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Oligo targeting for profiling drug resistance mutations in the parasitic trypanosomatids

Simone Altmann, Eva Rico, Sandra Carvalho, Melanie Ridgway, Anna Trenaman, Hannah Donnelly, Michele Tinti, Susan Wyllie, David Horn. Nucleic Acids..

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Vacancies

PDRA-Development of Automated Plate Based Chemistry

Job Reference: SLSC1118
Salary: £33,309 – £40,927

Closing Date: Monday, September 12, 2022

The Synthetic Methodologies Team at the DDU has a diverse remit including technology development, reaction optimisation, late stage functionalisation, biotransformation, compound management, flow, process, scale up and medicinal chemistry. The team supports medicinal chemistry efforts by delivering new technology and synthetic approaches to the medicinal chemistry teams taking synthetic chemistry development off the critical path.

We are looking for an enthusiastic and experienced synthetic organic chemist to join the team. With first class synthetic and organisation skills the successful candidate will have the chance to join the dynamic, multidisciplinary Drug Discovery Unit and enhance synthesis at…

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Senior Computational Chemist

Ref: SLSC1117

Salary: Grade 8 (£42,149 – £50,296)

Closing Date: Friday 2nd September, 2022

The DDU  are recruiting for a highly motivated and expert Senior Computational Chemist to join our Computational Chemistry team. At grade 8 of the University pay scale (currently £42,149 – £50,296), this is a high responsibility role that offers you the opportunity to play an influential role in shaping the direction of the Computational Chemistry team and to contribute to the DDU drug discovery effort working collaboratively with medicinal chemists, structural biologists, biologists and biophysicists. It also provides an opportunity to:

  • be a part of a world-leading university-based drug discovery group
  • contribute to developing in-depth…

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Head of Computational Chemistry, Drug Discovery Unit.

Job Reference: SLSC1111
Salary: Please refer to advert

Closing Date: Friday, September 9, 2022

Tenured position at Reader/ Professorial Level

We are seeking an experienced computational chemist and drug discoverer to be Head of Computational Chemistry in the Drug Discovery Unit (DDU) at the University of Dundee.

This is an exciting position to develop novel computational chemistry methodology (accessing our screening, structural and DMPK data) and apply it to live drug discovery programmes in infectious diseases affecting Low and Middle Income Countries and innovative targets in a range of human diseases.

This is a substantive leadership post in a highly collaborative environment. The successful applicant will be part…

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