Media

Publications

Para-site-seeing Catalogue

Floyd, A, Yeoman, H, Southern, J, Dillon, R, Cook, S, Fairlamb, A, Ferguson, M, Horn, D, MacLean, L, Manthri, S,..

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Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis

Michael Thomas, De Rycker M, Ajakane M, Crouch S, Campbell L, Daugan A, Fra G, Guerrero C, Mackenzie C, MacLean..

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Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic properties

Fersing C, Boudot C, Paoli-Lombardo R, Primas N, Pinault E, Hutter S, Castera-Ducros C, Kabri Y, Pedron J, Bourgeade-Delmas S,..

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Genome-scale functional profiling of cell cycle controls in African trypanosomes

Catarina A. Marques*, Michele Tinti*, Andrew Cassidy, David Horn bioRxiv 2020.07.16.206698; doi: https://doi.org/10.1101/2020.07.16.206698. This article is a preprint and has not been..

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Vacancies

Molecular Modeller

Job Reference: SLSC0784
Salary: Grade 7 (£32,817 – £40,322)

Closing Date: Sunday, October 25, 2020

The Mode of Action group are seeking to appoint a highly motivated and highly skilled molecular modeller. The MoA group is embedded within the Wellcome Centre for Anti-Infectives Research (WCAIR) at the University of Dundee. The vision for WCAIR is to tackle the urgent unmet medical need and lack of drug discovery research for Neglected Tropical Diseases (NTDs). WCAIR aims to integrate research in fundamental biology and translational research to deliver high-quality pre-clinical drug candidates for the treatment of NTDs.

The MoA group, led by Dr…

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PhD studentship with computational Chemistry Team

We are offering a 4 year PhD studentship on the topic Developing in silico Fragment Screening methodologies.

This will be based with the DDU Computational Chemistry Team led by Dr Fabio Zuccotto. Supervisors will be Prof Ian Gilbert and Prof Ulrich Zachariae.

Deadline for submissions is 31st October.

Applications must be made through School of Life Sciences application form. Please contact Dr Zuccotto (f.zuccotto@dundee.ac.uk) for further information.

Background

The process to develop new medicines stars with the identification of small molecules that can modulate a biological target or pathway associated to the disease. In…

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Molecular/Cellular Parasitologist

Job reference: SLSC0779

Salary: Grade 7 (£32,817-£40,322)

Closing date: Sunday 4 October

The Mode of Action group (MoA) are seeking to appoint a highly motivated postdoctoral researcher with appropriate skills in molecular and cell biology.

The MoA group, led by Dr Susan Wyllie, is focused on determining the mechanism of action and molecular targets of compounds that are phenotypically-active. To date this work has focused on kinetoplastid and Plasmodium parasites. We have developed an integrated drug target deconvolution strategy, employing an array of established and new methodologies encompassing high-throughput genetics, cell biology and chemical proteomics. We work closely with partners in academia and industry, and information…

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