Post-transcriptional reprogramming by thousands of mRNA untranslated regions in trypanosomes

Anna Trenaman, Michele Tinti, Richard J. Wall & David Horn Nat Commun 15, 8113 (2024). Abstract Although genome-wide polycistronic transcription places..

ResMAP-a saturation mutagenesis platform enabling parallel profiling of target-specific resistance-conferring mutations in Plasmodium

Richard J Wall , Stuart A MacGowan , Irene Hallyburton , Aisha J Syed , Sowmya Ajay Castro , Gourav..

The major surface protein of malaria sporozoites is GPI-anchored to the plasma membrane

Rupa Nagar, Stefano S Garcia Castillo, Maria Pinzon-Ortiz, Sharon Patray, Alida Coppi, Sachie Kanatani, Robert L Moritz, Kristian E Swearingen,..

A proposed pathway from D-glucose to D-arabinose in eukaryotes

Elda Iljazi, Rupa Nagar, Sabine Kuettel, Kieron Lucas, Arthur Crossman, Marie-Ange Badet-Denisot, Ronald W. Woodard, Michael A.J. Ferguson. Journal of..

Superior Anticancer and Antifungal Activities of New Sulfanyl-Substituted Niclosamide Derivatives

Ma, Jingyi, Dileepkumar Veeragoni, Hindole Ghosh, Nicole Mutter, Gisele Barbosa [1], Lauren Webster, Rainer Schobert, Wendy van de Sande, Prasad..

Generation of a bloodstream form Trypanosoma brucei double glycosyltransferase null mutant competent in receptor-mediated endocytosis of transferrin

Samuel M. Duncan, Carla Gilabert Carbajo, Rupa Nagar, Qi Zhong, Conor Breen, Michael A. J. Ferguson ,Calvin Tiengwe PLOS Pathogens..

Sterol 14-alpha demethylase (CYP51) activity in Leishmania donovani is likely dependent upon cytochrome P450 reductase 1

Lindsay B. Tulloch, Michele Tinti, Richard J. Wall, Stefan K. Weidt, Victoriano Corpas- Lopez, Gourav Dey, Terry K. Smith, Alan..

Synthesis of Nitrostyrylthiazolidine-2,4-dione Derivatives Displaying Antileishmanial Potential

Omar Khoumeri, Sébastien Hutter, Nicolas Primas, Caroline Castera-Ducros, Sandra Carvalho, Susan Wyllie, Mohamed Lotfi Efrit, Dimitri Fayolle, Marc Since, Patrice..

Accurate prediction of dynamic protein–ligand binding using P-score ranking

Peter E. G. F. Ibrahim, Fabio Zuccotto, Ulrich Zachariae, Ian Gilbert, Mike Bodkin J. Comput. Chem. 2024, 45(20), 1762. Abstract Protein–ligand binding prediction typically relies on docking..

Application of an NMR/Crystallography Fragment Screening Platform for the Assessment and Rapid Discovery of New HIV-CA Binding Fragments

Dr. Stuart Lang, Dr. Daniel A. Fletcher, Dr. Alain-Pierre Petit, Dr. Nicola Luise, Dr. Paul Fyfe, Dr. Fabio Zuccotto, Dr. David Porter, Dr. Anthony Hope, Dr. Fiona Bellany, Dr...

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