Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex.

Joana Faria, Lucy Glover, Sebastian Hutchinson, Cordula Boehm, Mark C. Field, David Horn. Nat Commun [Internet]. 2019;10(1):3023. Abstract The largest..

Burkholderia pseudomallei D‐alanine‐D‐alanine ligase; detailed characterisation and assessment of a potential antibiotic drug target

Díaz-Sáez L, Torrie LS, McElroy SP, Gray D, Hunter WN FEBS J [Internet]. 2019;286(22):4509–24 Abstract Burkholderia pseudomallei is a serious, difficult to..

Substituted aminoacetamides as novel leads for malaria

Neil R. Norcross, Caroline Wilson, Beatriz Baragaña, Irene Hallyburton, Maria Osuna-Cabello, Suzanne Norval, Jennifer Riley, Daniel Fletcher, Robert Sinden, Michael..

Identification of inhibitors of an unconventional Trypanosoma brucei kinetochore kinase

Leah S. Torrie, Fabio Zuccotto, David A. Robinson, David W. Gray, Ian H. Gilbert , Manu De Rycker PLoS ONE..

Phosphatidylcholine synthesis through cholinephosphate cytidylyltransferase is dispensable in Leishmania major.

Moitra S, Pawlowic MC, Hsu F, Zhang K. Sci Rep [Internet]. 2019;9(1):7602 Abstract Phosphatidylcholine (PC) is a major cell..

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Susan Wyllie, Stephen Brand, Michael Thomas, Manu De Rycker, Chun-wa Chung, Imanol Pena, Ryan P. Bingham, Juan A. Bueren-Calabuig, Juan..

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Beatriz Baragaña, Barbara Forte, Ryan Choi, Stephen Nakazawa Hewitt, Juan A. Bueren-Calabuig, João Pedro Pisco, Caroline Peet, David M. Dranow,..

Nongenotoxic 3-Nitroimidazo[1,2-a]pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity

Fersing C, Basmaciyan L, Boudot C, Pedron J, Hutter S, Cohen A, et al WCAIR contributors : Rachel Milne, Susan..

Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani.

Victoriano Corpas-Lopez, Sonia Moniz, Michael Thomas, Richard J. Wall, Leah S. Torrie, Dorothea Zander-Dinse, Michele Tinti, Stephen Brand, Laste Stojanovski,..

Diversity-oriented synthesis of bicyclic fragments containing privileged azines.

Luise N, Wyatt PG Bioorg Med Chem Lett [Internet]. 2019;29(2):248–51 Abstract An innovative and efficient reagent- and scaffold-based diversity oriented..

« Previous 1 2 3 4 … 6 Next »

Publications