Superior Anticancer and Antifungal Activities of New Sulfanyl-Substituted Niclosamide Derivatives

Ma, Jingyi, Dileepkumar Veeragoni, Hindole Ghosh, Nicole Mutter, Gisele Barbosa [1], Lauren Webster, Rainer Schobert, Wendy van de Sande, Prasad..

Generation of a bloodstream form Trypanosoma brucei double glycosyltransferase null mutant competent in receptor-mediated endocytosis of transferrin

Samuel M. Duncan, Carla Gilabert Carbajo, Rupa Nagar, Qi Zhong, Conor Breen, Michael A. J. Ferguson ,Calvin Tiengwe PLOS Pathogens..

Sterol 14-alpha demethylase (CYP51) activity in Leishmania donovani is likely dependent upon cytochrome P450 reductase 1

Lindsay B. Tulloch, Michele Tinti, Richard J. Wall, Stefan K. Weidt, Victoriano Corpas- Lopez, Gourav Dey, Terry K. Smith, Alan..

Synthesis of Nitrostyrylthiazolidine-2,4-dione Derivatives Displaying Antileishmanial Potential

Omar Khoumeri, Sébastien Hutter, Nicolas Primas, Caroline Castera-Ducros, Sandra Carvalho, Susan Wyllie, Mohamed Lotfi Efrit, Dimitri Fayolle, Marc Since, Patrice..

Accurate prediction of dynamic protein–ligand binding using P-score ranking

Peter E. G. F. Ibrahim, Fabio Zuccotto, Ulrich Zachariae, Ian Gilbert, Mike Bodkin J. Comput. Chem. 2024, 45(20), 1762. Abstract Protein–ligand binding prediction typically relies on docking..

Application of an NMR/Crystallography Fragment Screening Platform for the Assessment and Rapid Discovery of New HIV-CA Binding Fragments

Dr. Stuart Lang, Dr. Daniel A. Fletcher, Dr. Alain-Pierre Petit, Dr. Nicola Luise, Dr. Paul Fyfe, Dr. Fabio Zuccotto, Dr. David Porter, Dr. Anthony Hope, Dr. Fiona Bellany, Dr...

Acute response to pathogens in the early human placenta at single-cell resolution

Regina Hoo, Elias R. Ruiz-Morales, Iva Kelava, Mukul Rawat, Cecilia Icoresi Mazzeo, Elizabeth Tuck, Carmen Sancho-Serra, Sara Chelaghma, Alexander V...

The first Cryptosporidium meeting: a concerted effort to fight cryptosporidiosis

Wes van Voorhis, Joyce Siwila, Jessica C. Kissinger, Natalia Bayona Vásquez, Guy Robinson, Rodrigo Baptista, Asis Khan, Amandine Guérin, Yi-Wei..

Identification and Validation of Compounds Targeting Leishmania major Leucyl-Aminopeptidase M17

Mirtha E. Aguado, Sandra Carvalho, Mario E. Valdés-Tresanco, De Lin, Norma Padilla-Mejia, Victoriano Corpas-Lopez, Martina Tesařová, Julius Lukeš, David Gray,..

Validation of Trypanosoma cruzi inactivation techniques for laboratory use

Lorna M. MacLean , Mark Ariyanayagam, Lalitha Sastry, Christy Paterson, Manu De Rycker, Alan H. Fairlamb PLOS ONE 19(4): e0300021. https://doi.org/10.1371/journal.pone.0300021..

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