Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation

Selina Bopp, Charisse Flerida A. Pasaje, Robert L. Summers, Pamela Magistrado-Coxen, Kyra A. Schindler, Victoriano Corpas-Lopez, Tomas Yeo, Sachel Mok,..

Assessment of the drugability of initial malaria infection through miniaturized sporozoite assays and high-throughput screening

Marie Miglianico, Judith M. Bolscher, Martijn W. Vos, Karin J. M. Koolen, Marloes de Bruijni, Deeya S. Rajagopal, Emily Chen,..

The role of invariant surface glycoprotein 75 in xenobiotic acquisition by African trypanosomes

Alexandr Makarov, Jakub Began, Ileana Corvo Mautone, Erika Pinto, Liam Ferguson, Martin Zoltner, Sebastian Zoll and Mark C. Field. Microbial..

Impact of inherent biases built into proteomic techniques: Proximity labeling and affinity capture compared

Claudia Maria do Nascimento Moreira, Cristina D. Kelemen, Samson O. Obado , Farnaz Zahedifard , Ning Zhang , Fabiola B...

Ethanolaminephosphate cytidyltransferase is essential for survival, lipid homeostasis and stress tolerance in Leishmania major

Somrita Basu, Mattie Pawlowic, Fong-Fu Hsu, Geoff Thomas, Kai Zhang. bioRxiv 2023.01.10.523530; doi: https://doi.org/10.1101/2023.01.10.523530 This article is a preprint and has not been..

Chemical pulldown combined with mass spectrometry to identify the molecular targets of antimalarials in cell-free lysates

Robert J Smith , Rachel Milne , Victoriano Corpas Lopez , Natalie Wiedemar , Gourav Dey , Aisha J Syed..

Antileishmanial Activities of (Z)-2-(Nitroimidazolylmethylene)-3(2H)-Benzofuranones: Synthesis, In Vitro Assessment, and Bioactivation by NTR 1 and 2

Latifeh Navidpour, Marta Lopes Lima, Rachel Milne, Susan Wyllie, Narges Hadj-esfandiari, Muhammad Iqbal Choudhary, Samreen Khan, Sammer Yousuf Antimicrobial Agents..

CRISPR-based oligo recombineering prioritizes apicomplexan cysteines for drug discovery

H. J. Benns, M. Storch, J. A. Falco, F. R. Fisher, F. Tamaki, E. Alves, C. J. Wincott, R. Milne,..

Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs

Simon R. Green, Susan H. Davis, Sebastian Damerow, Curtis A. Engelhart, Michael Mathieson, Beatriz Baragaña, David A. Robinson, Jevgenia Tamjar,..

Common and unique features of glycosylation and glycosyltransferases in African trypanosomes

Samuel M. Duncan, Michael A.J. Ferguson. Biochem J (2022) 479 (17): 1743–1758. Abstract Eukaryotic protein glycosylation is mediated by glycosyl- and..

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