Publications

Roles of Glycans in Protozoal Host-Parasite Interactions

Giulia Bandini and Michael A.J. Ferguson. Encyclopedia of Cell Biology: Volume 1-6, Second Edition, Volume 4, Pages 363 - 3721..

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Ethanolaminephosphate cytidyltransferase is essential for survival, lipid homeostasis and stress tolerance in Leishmania major

Somrita Basu, Mattie Pawlowic, Fong-Fu Hsu, Geoff Thomas, Kai Zhang. bioRxiv 2023.01.10.523530; doi: https://doi.org/10.1101/2023.01.10.523530 This article is a preprint and has not been..

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Chemical pulldown combined with mass spectrometry to identify the molecular targets of antimalarials in cell-free lysates

Robert J Smith , Rachel Milne , Victoriano Corpas Lopez , Natalie Wiedemar , Gourav Dey , Aisha J Syed..

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Antileishmanial Activities of (Z)-2-(Nitroimidazolylmethylene)-3(2H)-Benzofuranones: Synthesis, In Vitro Assessment, and Bioactivation by NTR 1 and 2

Latifeh Navidpour, Marta Lopes Lima, Rachel Milne, Susan Wyllie, Narges Hadj-esfandiari, Muhammad Iqbal Choudhary, Samreen Khan, Sammer Yousuf Antimicrobial Agents..

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CRISPR-based oligo recombineering prioritizes apicomplexan cysteines for drug discovery

H. J. Benns, M. Storch, J. A. Falco, F. R. Fisher, F. Tamaki, E. Alves, C. J. Wincott, R. Milne,..

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Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs

Simon R. Green, Susan H. Davis, Sebastian Damerow, Curtis A. Engelhart, Michael Mathieson, Beatriz Baragaña, David A. Robinson, Jevgenia Tamjar,..

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Common and unique features of glycosylation and glycosyltransferases in African trypanosomes

Samuel M. Duncan, Michael A.J. Ferguson. Biochem J (2022) 479 (17): 1743–1758. Abstract Eukaryotic protein glycosylation is mediated by glycosyl- and..

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Genome-scale RNA interference profiling of Trypanosoma brucei cell cycle progression defects.

Catarina A. Marques, Melanie Ridgway, Michele Tinti, Andrew Cassidy & David Horn Nat Commun 13, 5326 (2022). https://doi.org/10.1038/s41467-022-33109-y Abstract Trypanosomatids, which..

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Drug discovery research in Ghana, challenges, current efforts, and the way forward

Richard Kwamla Amewu , Patrick Amoateng, Patrick Kobina Arthur, Prince Asare, Isaac Asiamah, Daniel Boamah, Isaac Darko Otchere, Cedric Dzidzor..

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Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase

Rachel Milne, Natalie Wiedemar, Victoriano Corpas-Lopez, Eoin Moynihan, Richard J. Wall, Alice Dawson, David A. Robinson, Sharon M. Shepherd, Robert..

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