Publications

Acute response to pathogens in the early human placenta at single-cell resolution

Regina Hoo, Elias R. Ruiz-Morales, Iva Kelava, Mukul Rawat, Cecilia Icoresi Mazzeo, Elizabeth Tuck, Carmen Sancho-Serra, Sara Chelaghma, Alexander V...

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The first Cryptosporidium meeting: a concerted effort to fight cryptosporidiosis

Wes van Voorhis, Joyce Siwila, Jessica C. Kissinger, Natalia Bayona Vásquez, Guy Robinson, Rodrigo Baptista, Asis Khan, Amandine Guérin, Yi-Wei..

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Identification and Validation of Compounds Targeting Leishmania major Leucyl-Aminopeptidase M17

Mirtha E. Aguado, Sandra Carvalho, Mario E. Valdés-Tresanco, De Lin, Norma Padilla-Mejia, Victoriano Corpas-Lopez, Martina Tesařová, Julius Lukeš, David Gray,..

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Validation of Trypanosoma cruzi inactivation techniques for laboratory use

Lorna M. MacLean , Mark Ariyanayagam, Lalitha Sastry, Christy Paterson, Manu De Rycker, Alan H. Fairlamb PLOS ONE 19(4): e0300021. https://doi.org/10.1371/journal.pone.0300021..

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Phylogenomic reconstruction of Cryptosporidium spp. captured directly from clinical samples reveals extensive genetic diversity

A. Khan, E.V.C. Alves-Ferreira, H. Vogel, S. Botchie, S I. Ayi, M.C. Pawlowic, G. Robinson, R.M. Chalmers, H. Lorenzi, M.E. Grigg bioRxiv  2024.04.17.589752  doi: https://doi.org/10.1101/2024.04.17.589752 Abstract Cryptosporidium is a leading cause of severe diarrhea and mortality in young children and..

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The bloodstream form of Trypanosoma brucei displays non-canonical gluconeogenesis

Kovářová, Julie; Moos, Martin; Barrett, Michael P.; Horn, David; Zíková, Alena. PLOS Neglected Tropical Diseases 18(2): e0012007 Abstract Trypanosoma brucei..

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Identification of a potent and selective LAPTc inhibitor by RapidFire-Mass Spectrometry, with antichagasic activity

Izquierdo, Maikel; Lin, De; O’Neill, Sandra; Webster, Lauren A.; Paterson, Christy; Thomas, John; Aguado, Mirtha Elisa; Araújo, Enrique Colina; Alpízar-Pedraza,..

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Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism

A. Kenneth MacLeod, Kevin-Sebastien Coquelin, Leticia Huertas, Frederick R.C. Simeons, Jennifer Riley, Patricia Casado, Laura Guijarro, Ruth Casanueva, Laura Frame,..

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Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase

Stanley C. Xie, Yinuo Wang, Craig J. Morton, Riley D. Metcalfe, Con Dogovski, Charisse Flerida A. Pasaje, Elyse Dunn, Madeline..

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Design of the Global Health chemical diversity library v2 for screening against infectious diseases

Wilson, Caroline; Gardner, J. Mark F.; Gray, David W.; Baragana, Beatriz; Wyatt, Paul G.; Cookson, Alex; Thompson, Stephen; Mendoza-Martinez, Cesar;..

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