Publications

Generation of a bloodstream form Trypanosoma brucei double glycosyltransferase null mutant competent in receptor-mediated endocytosis of transferrin

Samuel M. Duncan, Carla Gilabert Carbajo, Rupa Nagar, Qi Zhong, Conor Breen, Michael A. J. Ferguson ,Calvin Tiengwe PLOS Pathogens..

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Sterol 14-alpha demethylase (CYP51) activity in Leishmania donovani is likely dependent upon cytochrome P450 reductase 1

Lindsay B. Tulloch, Michele Tinti, Richard J. Wall, Stefan K. Weidt, Victoriano Corpas- Lopez, Gourav Dey, Terry K. Smith, Alan..

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Synthesis of Nitrostyrylthiazolidine-2,4-dione Derivatives Displaying Antileishmanial Potential

Omar Khoumeri, Sébastien Hutter, Nicolas Primas, Caroline Castera-Ducros, Sandra Carvalho, Susan Wyllie, Mohamed Lotfi Efrit, Dimitri Fayolle, Marc Since, Patrice..

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Accurate prediction of dynamic protein–ligand binding using P-score ranking

Peter E. G. F. Ibrahim,  Fabio Zuccotto,  Ulrich Zachariae,  Ian Gilbert,  Mike Bodkin J. Comput. Chem. 2024, 45(20), 1762. Abstract Protein–ligand binding prediction typically relies on docking..

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Application of an NMR/Crystallography Fragment Screening Platform for the Assessment and Rapid Discovery of New HIV-CA Binding Fragments

Dr. Stuart Lang,  Dr. Daniel A. Fletcher,  Dr. Alain-Pierre Petit,  Dr. Nicola Luise,  Dr. Paul Fyfe,  Dr. Fabio Zuccotto,  Dr. David Porter,  Dr. Anthony Hope,  Dr. Fiona Bellany,  Dr...

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Acute response to pathogens in the early human placenta at single-cell resolution

Regina Hoo, Elias R. Ruiz-Morales, Iva Kelava, Mukul Rawat, Cecilia Icoresi Mazzeo, Elizabeth Tuck, Carmen Sancho-Serra, Sara Chelaghma, Alexander V...

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The first Cryptosporidium meeting: a concerted effort to fight cryptosporidiosis

Wes van Voorhis, Joyce Siwila, Jessica C. Kissinger, Natalia Bayona Vásquez, Guy Robinson, Rodrigo Baptista, Asis Khan, Amandine Guérin, Yi-Wei..

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Identification and Validation of Compounds Targeting Leishmania major Leucyl-Aminopeptidase M17

Mirtha E. Aguado, Sandra Carvalho, Mario E. Valdés-Tresanco, De Lin, Norma Padilla-Mejia, Victoriano Corpas-Lopez, Martina Tesařová, Julius Lukeš, David Gray,..

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Validation of Trypanosoma cruzi inactivation techniques for laboratory use

Lorna M. MacLean , Mark Ariyanayagam, Lalitha Sastry, Christy Paterson, Manu De Rycker, Alan H. Fairlamb PLOS ONE 19(4): e0300021. https://doi.org/10.1371/journal.pone.0300021..

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Phylogenomic reconstruction of Cryptosporidium spp. captured directly from clinical samples reveals extensive genetic diversity

A. Khan, E.V.C. Alves-Ferreira, H. Vogel, S. Botchie, S I. Ayi, M.C. Pawlowic, G. Robinson, R.M. Chalmers, H. Lorenzi, M.E. Grigg bioRxiv  2024.04.17.589752  doi: https://doi.org/10.1101/2024.04.17.589752 Abstract Cryptosporidium is a leading cause of severe diarrhea and mortality in young children and..

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