New 8-Nitroquinolinone Derivative Displaying Submicromolar in Vitro Activities against Both Trypanosoma brucei and cruzi

Julien Pedron, Clotilde Boudot, Jean-Yves Brossas, Emilie Pinault, Sandra Bourgeade-Delmas, Alix Sournia-Saquet, Elisa Boutet-Robinet, Alexandre Destere, Antoine Tronnet, Justine Bergé,..

The Qi site of cytochrome b is a promiscuous drug target in Trypanosoma cruzi and Leishmania donovani

Richard J Wall, Sandra Carvalho, Rachel Milne, Juan A. Bueren-Calabuig, Sonia Moniz, Juan Cantizani-Perez, Lorna MacLean, Albane Kessler, Ignacio Cotillo,..

Setting Our Sights on Infectious Diseases

De Rycker, Manu, Horn, David, Aldridge, Bree, Amewu, Richard K, Barry, Clifton E, Buckner, Frederick S, Cook, Sarah, Ferguson, Michael..

Genetic Manipulation of Cryptosporidium parvum with CRISPR/Cas9

Sateriale A, Pawlowic M, Vinayak S, Brooks C, Striepen B In: Mead JR, Arrowood MJ, editors. Cryptosporidium: Methods and Protocols..

Evolution of late steps in exocytosis: conservation and specialization of the exocyst complex

Boehm C, Field MC Wellcome Open Res. 2019;4(112). [version 2; peer review: 3 approved] Abstract Background: The eukaryotic endomembrane system..

A platform for target prediction of phenotypic screening hit molecules

Homeyer N, van Deursen R, Ochoa-Montaño B, Heikamp K, Ray P, Zuccotto F, Blundell T, Gilbert I. J Mol Graph..

Genetic ablation of purine salvage in Cryptosporidium parvum reveals nucleotide uptake from the host cell

Mattie C. Pawlowic, Mastanbabu Somepalli, Adam Sateriale, Gillian T. Herbert, Alexis R. Gibson, Gregory D. Cuny, Lizbeth Hedstrom, and Boris..

Proteome turnover in the bloodstream and procyclic forms of Trypanosoma brucei measured by quantitative proteomics

Tinti, M, Güther, MLS, Crozier, TWM, Lamond, AI, Ferguson, MAJ Wellcome Open Res. 2019;4(152) [version 1; peer review: 3 approved]..

Trypanosoma cruzi phosphomannomutase and guanosine diphosphate-mannose pyrophosphorylase ligandability assessment

Filip Zmuda, Sharon M. Shepherd, Michael A. J. Ferguson, David. W. Gray, Leah S. Torrie, Manu De Rycker Antimicrob Agents..

A post-transcriptional respiratome regulon in trypanosomes

Anna Trenaman, Lucy Glover, Sebastian Hutchinson and David Horn Nucleic Acids Res. 2019 Jul 26; 47(13): 7063–7077. Published online 2019..

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