Profiling of Antileishmanial Efficacy and Resistance in the Related Kinetoplastid Parasite Trypanosoma brucei .

Collett CF, Kitson C, Baker N, Steele-Stallard HB, Santrot M-V, Hutchinson S, Horn D, Alsford S. Antimicrob Agents Chemother [Internet]...

Identification of inhibitors of an unconventional Trypanosoma brucei kinetochore kinase

Leah S. Torrie, Fabio Zuccotto, David A. Robinson, David W. Gray, Ian H. Gilbert , Manu De Rycker PLoS ONE..

Phosphatidylcholine synthesis through cholinephosphate cytidylyltransferase is dispensable in Leishmania major.

Moitra S, Pawlowic MC, Hsu F, Zhang K. Sci Rep [Internet]. 2019;9(1):7602 Abstract Phosphatidylcholine (PC) is a major cell..

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Susan Wyllie, Stephen Brand, Michael Thomas, Manu De Rycker, Chun-wa Chung, Imanol Pena, Ryan P. Bingham, Juan A. Bueren-Calabuig, Juan..

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Beatriz Baragaña, Barbara Forte, Ryan Choi, Stephen Nakazawa Hewitt, Juan A. Bueren-Calabuig, João Pedro Pisco, Caroline Peet, David M. Dranow,..

Nongenotoxic 3-Nitroimidazo[1,2-a]pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity

Fersing C, Basmaciyan L, Boudot C, Pedron J, Hutter S, Cohen A, et al WCAIR contributors : Rachel Milne, Susan..

Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani.

Victoriano Corpas-Lopez, Sonia Moniz, Michael Thomas, Richard J. Wall, Leah S. Torrie, Dorothea Zander-Dinse, Michele Tinti, Stephen Brand, Laste Stojanovski,..

Diversity-oriented synthesis of bicyclic fragments containing privileged azines.

Luise N, Wyatt PG Bioorg Med Chem Lett [Internet]. 2019;29(2):248–51 Abstract An innovative and efficient reagent- and scaffold-based diversity oriented..

Gluconeogenesis using glycerol as a substrate in bloodstream-form Trypanosoma brucei.

Kovářová J, Nagar R, Faria J, Ferguson MAJ, Barrett MP, Horn D. PLOS Pathog. 2018;14(12):e1007475. Bloodstream form African trypanosomes are..

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Michael G. Thomas, Manu De Rycker, Myriam Ajakane, Sébastian Albrecht, Ana Isabel Álvarez-Pedraglio, Markus Boesche, Stephen Brand, Lorna Campbell, Juan..

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