Plasmodium Kinases as Potential Drug Targets for Malaria: Challenges and Opportunities.

Lauren B Arendse, Susan Wyllie, Kelly Chibale, Ian H Gilbert. ACS Infect Dis. 2021 Mar 12;7(3):518-534. doi: 10.1021/acsinfecdis.0c00724. Epub 2021..

Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry

Lesley-Anne Pearson, Charlotte J Green, De Lin, Alain-Pierre Petit, David W Gray, Victoria H Cowling, Euan A F Fordyce. SLAS..

De Novo Synthesis of Phosphatidylcholine Is Essential for the Promastigote But Not Amastigote Stage in Leishmania major

Samrat Moitra, Somrita Basu, Mattie Pawlowic, Fong-fu Hsu and Kai Zhang Front. Cell. Infect. Microbiol., 12 March 2021 | https://doi.org/10.3389/fcimb.2021.647870..

MalDA, Accelerating Malaria

Tuo Yang, Sabine Ottilie, Eva S Istvan, Karla P Godinez-Macias, Amanda K Lukens, Beatriz Baragaña, Brice Campo, Chris Walpole, Jacquin..

A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research

Suzannah J. Rihn , Andres Merits , Siddharth Bakshi , Matthew L. Turnbull , Arthur Wickenhagen , Akira J. T...

Structure-Activity Relationships of Pyrazolo[1,5- a]pyrimidin-7(4 H)-ones as Antitubercular Agents

Sangmi Oh, M Daben J Libardo, Shaik Azeeza, Gary T Pauly, Jose Santinni O Roma, Andaleeb Sajid, Yoshitaka Tateishi, Caroline..

Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes

Joana Faria, Vanessa Luzak, Laura S. M. Müller, Benedikt G. Brink, Sebastian Hutchinson, Lucy Glover, David Horn & T. Nicolai..

Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth

Peter C. Ray, Margaret Huggett, Penelope A. Turner, Malcolm Taylor, Laura A. T. Cleghorn, Julie Early, Anuradha Kumar, Shilah A...

Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site

Vitor Mendes, Simon R Green, Joanna C Evans, Jeannine Hess, Michal Blaszczyk , Christina Spry, Owain Bryant , James Cory-Wright..

Antitubercular 2-Pyrazolylpyrimidinones: Structure–Activity Relationship and Mode-of-Action Studies

Candice Soares de Melo, Vinayak Singh, Alissa Myrick, Sandile B. Simelane, Dale Taylor, Christel Brunschwig, Nina Lawrence, Dirk Schnappinger, Curtis..

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