Vacancies – Join Team

Vacancies

Postdoctoral Research Assistant (Synthetic Methodologies)

Reference Number SLSC0795

Grade Grade 7 (£32,817 – £40,322)

Closing Date 26 November 2020

The Drug Discovery Unit (DDU) within the Wellcome Centre for Anti-Infectives Research is seeking a driven, top tier postdoctoral scientist to join the  Synthetic Methodologies Team to develop approaches and methodology to broaden the chemistry methods and strategies available to the DDU medicinal chemistry teams within its drug discovery projects.

The Role

Exploration of chemical diversity from fragments and hits using a common intermediate: – This position is to develop and establish in-house expertise in rapid fragment diversification. This project will use literature searching and automated synthesis route evaluation programmes to identify multiple reactions that can…

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Medicinal Chemistry Team Leader

Reference Number SLSC0793

Grade Grade 8 (£41,526 – £49,553)

Closing Date 14 November 2020

We are seeking a highly motivated and experienced medicinal chemist with experience in the BioPharma industry or similar, for a team leader role within the Drug Discovery Unit (DDU). The successful applicant will join a dynamic and multidisciplinary group that covers all aspects of drug discovery up to candidate selection. Work will cover all aspects of early drug discovery from hit validation through to lead optimisation. The appointee will plan and lead multidisciplinary projects, line manage and co-ordinate the work of a team of chemists and drive interactions between medicinal chemists, biologists, computational chemists and drug…

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Junior Data Manager / Data Technician

Reference Number SLSC0773

Grade: Grade 5 or 6 depending on experience, please see below

Closing Date:  11 November 2020

The Drug Discovery Unit (DDU) is a fully integrated drug discovery operation based within a world class Life Sciences research environment. The DDU works on both validation of novel drug targets across a range of therapeutics areas and developing new medicines for neglected diseases (TB, malaria, cryptosporidiosis, leishmaniasis and Chagas disease). The DDU works to Biotech style philosophy and standards, incorporating dynamic, goal driven project management. The DDU has a proven track record of partnering/licencing new drug targets with industry and delivering pre-clinical candidates for neglected diseases.



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Assay Development Scientist (Biochemistry) / Enzymologist

Reference Number SLSC0772

Grade Grade 7 (£32,817 – £40,322)

Closing Date: 9 November 2020

We are looking for a highly motivated enzymologist / biochemist to join the Wellcome Centre for Anti-Infectives Research. The appointee will work jointly between the Mode of Action Group and the Apicomplexan team within the Drug Discovery Unit. Both groups work to identify new drug targets that can be exploited to develop new drugs for tropical diseases, such as malaria, Chagas’ disease and visceral leishmaniasis. WCAIR is housed in state-of-the-art facilities and has cutting-edge equipment and automation to support anti-infectives research.

The post holder will join a multi-disciplinary…

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Chemical Inventory Assistant

Reference Number: SLSC0786

Grade 4 (£19,612 – £22,417)

Closing Date:  10 November 2020

The Drug Discovery Unit (DDU) are recruiting for an exceptional individual to join us as a Chemical Inventory Assistant. The post will be primarily laboratory based and will support our chemistry teams in and maintaining the >20, 000 reagents and compounds prepared in Dundee and stored in the chemistry reagent store. Working closely with the Chemical Inventory Manager you will be required to liaise with Medicinal Chemistry, compound logistics, and store personnel to ensure compounds and reagents are handled, used and dispensed as efficiently as possible.

Your responsibilities
Working with the Chemical Inventory Manager you will…

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PhD studentship with computational Chemistry Team

We are offering a 4 year PhD studentship on the topic Developing in silico Fragment Screening methodologies.

This will be based with the DDU Computational Chemistry Team led by Dr Fabio Zuccotto. Supervisors will be Prof Ian Gilbert and Prof Ulrich Zachariae.

Deadline for submissions is 31st October.

Applications must be made through School of Life Sciences application form. Please contact Dr Zuccotto (f.zuccotto@dundee.ac.uk) for further information.

Background

The process to develop new medicines stars with the identification of small molecules that can modulate a biological target or pathway associated to the disease. In…

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