How to…

This series will cover common in vitro drug metabolism and pharmacokinetic (DMPK) experiments. This series of animated videos will take you through the basic principles on how to set up, perform and analyse any given assay.

Suspension Hepatocyte Assay

Drugs are can be metabolised via the liver, but how do scientists determine how and what is responsible for this inside of the liver.  The following video will take you through the set-up, procedure and analysis of the cryopreserved suspension hepatocyte assay

Plasma Protein Binding Assay (PPB)

Plasma protein binding is one way of determining how much of your chosen drug is free, unbound from proteins, to cause its therapeutic response. In this video, you will be taken through how to perform the plasma protein binding assay in the lab.