Publications

Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes

Martin Zoltner, Gustavo D Campagnaro, Gergana Taleva, Alana Burrell, Michela Cerone, Ka-Fai Leung, Fiona Achcar, David Horn, Sue Vaughan, Catarina..

Read More

Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase

Leah S. Torrie, David A. Robinson, Michael Thomas, Judith V Hobrath, Sharon M Shepherd, John M. Post, Eun-Jung Ko, Rafael..

Read More

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease

Justin R. Harrison, Sandipan Sarkar, Shahienaz Hampton, Jennifer Riley, Laste Stojanovski, Christer Sahlberg, Pia Appelqvist, Jessey Erath, Vinodhini Mathan, Ana..

Read More

A One Health Approach to Tackle Cryptosporidiosis

Elisabeth A.Innes, Rachel M.Chalmers, BethWells, Mattie C.Pawlowic . Trends in Parasitology 2020 vol: 36 (3) pp: 290-303 DOI: 10.1016/J.PT.2019.12.016 Review Highlights Development of..

Read More

PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis

Qinglan Wang, Helena I. M. Boshoff, Justin R. Harrison, Peter C. Ray, Simon R. Green, Paul G. Wyatt, Clifton E. Barry III. Science ..

Read More

New 8-Nitroquinolinone Derivative Displaying Submicromolar in Vitro Activities against Both Trypanosoma brucei and cruzi

Julien Pedron, Clotilde Boudot, Jean-Yves Brossas, Emilie Pinault, Sandra Bourgeade-Delmas, Alix Sournia-Saquet, Elisa Boutet-Robinet, Alexandre Destere, Antoine Tronnet, Justine Bergé,..

Read More

The Qi site of cytochrome b is a promiscuous drug target in Trypanosoma cruzi and Leishmania donovani

Richard J Wall, Sandra Carvalho, Rachel Milne, Juan A. Bueren-Calabuig, Sonia Moniz, Juan Cantizani-Perez, Lorna MacLean, Albane Kessler, Ignacio Cotillo,..

Read More

Setting Our Sights on Infectious Diseases

De Rycker, Manu, Horn, David, Aldridge, Bree, Amewu, Richard K, Barry, Clifton E, Buckner, Frederick S, Cook, Sarah, Ferguson, Michael..

Read More

Genetic Manipulation of Cryptosporidium parvum with CRISPR/Cas9

Sateriale A, Pawlowic M, Vinayak S, Brooks C, Striepen B In: Mead JR, Arrowood MJ, editors. Cryptosporidium: Methods and Protocols..

Read More

Evolution of late steps in exocytosis: conservation and specialization of the exocyst complex

Boehm C, Field MC Wellcome Open Res. 2019;4(112). [version 2; peer review: 3 approved] Abstract Background: The eukaryotic endomembrane system..

Read More