Utilizing thermal proteome profiling to identify the molecular targets of anti-leishmanial compounds

Victoriano Corpas-Lopez, Susan Wyllie. STAR Protocols,2021, Volume 2, Issue 3, 100704 doi.org/10.1016/j.xpro.2021.100704. Abstract Here, we detail our optimized protocol for..

An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei

Giulia Bandini, Sebastian Damerow, Maria Lucia Sempaio Güther, Hongjie Guo, Angela Mehlert, Jose Carlos Paredes Franco, Stephen Beverley, Michael A..

Monocyclic Nitro-heteroaryl Nitrones with Dual Mechanism of Activation: Synthesis and Antileishmanial Activity

Juliana da Silva Pacheco, Débora de Souza Costa, Edézio Ferreira Cunha-Júnior, Valter Viana Andrade-Neto, Alan H. Fairlamb, Susan Wyllie, Marília..

Automated Phylogenetic Analysis Using Best Reciprocal BLAST

Erin R Butterfield , James C Abbott , Mark C Field In: de Pablos L.M., Sotillo J. (eds) Parasite Genomics...

Elimination of GPI2 suppresses glycosylphosphatidylinositol GlcNAc transferase activity and alters GPI glycan modification in Trypanosoma brucei

Aurelio Jenni, Sebastian Knüsel, RupaNagar, Mattias Benninger, Robert Häner, Michael A.J.Ferguson, Isabel Roditi, Anant K. Menon, Peter Bütikofer. Journal of..

Polysomal mRNA Association and Gene Expression in Trypanosoma brucei

Michele Tinti , Anna Kelner-Miron, Lizzie J. Marriott, Michael A.J. Ferguson. Wellcome Open Research 2021 vol 6, Article no. 36...

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

Robert L.Summers, Charisse Flerida A.Pasaje, Joao P.Pisco, Josefine Striepen, Madeline R.Luth, Krittikorn Kumpornsin, Emma F.Carpenter, Justin T.Munro, De Lin, Andrew..

Identification of Resistance Determinants for a Promising Antileishmanial Oxaborole Series

Magali Van den Kerkhof, Philippe Leprohon, Dorien Mabille , Sarah Hendrickx, Lindsay B. Tulloch, Richard J. Wall, Susan Wyllie, Eric Chatelain,..

Expression in Escherichia coli, purification and kinetic characterization of LAPLm, a Leishmania major M17-aminopeptidase

Mirtha Elisa Aguadoa, Maikel González-Matosa, Maikel Izquierdo*, Juan Quintana, Mark C. Field, Jorge González-Bacerioa* Protein Expression and Purification, (2021), 105877,..

Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation

Karolina Michalska, Robert Jedrzejczak, Jacek Wower, Changsoo Chang, Beatriz Baragaña, Ian H Gilbert, Barbara Forte, Andrzej Joachimiak Nucleic Acids Research,..

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