DDU Medicinal Chemistry Team leader

Job Reference:  SLSC0856
Salary:  Grade 8 (£41,526 – £49,553)
Closing DateSunday, April 11, 2021

The Drug Discovery Unit is a globally acknowledged centre of excellence for drug discovery. The DDU collaborates with partners to translate world-class biology research into novel drug targets and candidate drugs to address unmet medical need across our two areas of activity, Diseases of the Developing World and Innovative Targets Portfolio.We are recruiting for an exceptional individual to join us as a Medicinal Chemistry Team Leader within our Drug Discovery Unit (DDU).

We are seeking a highly motivated and experienced medicinal chemist with experience in the BioPharma industry or similar, for a team leader role within the Drug Discovery Unit (DDU). The successful applicant will join a dynamic and multidisciplinary group that covers all aspects of drug discovery up to candidate selection. Work will cover all aspects of early drug discovery from hit validation through to lead optimisation. The appointee will plan and lead multidisciplinary projects, line manage and co-ordinate the work of a team of chemists and drive interactions between medicinal chemists, biologists, computational chemists and drug metabolism & pharmacokinetics experts within the DDU team.

Your priorities will include
  • Work within interdisciplinary teams and actively contribute to drug discovery projects at all stages.
  • Day-to-day responsibility of delivering the project goals.
  • Lead hit validation to lead optimisation medicinal chemistry projects, to identify leads demonstrating appropriate pharmaceutical properties and efficacy in disease models.
  • Lead and mentor a team of medicinal chemists.
  • Analyse assay and pharmacokinetic data to design and synthesise target compounds
  • Write reports, presentations and publications
  • Oversee outsourced chemistry.
Who we’re looking for
  • Candidates must be professionally qualified with a PhD in a chemical science related discipline or alternatively a BSc in a chemistry related subject with subsequent substantial relevant drug discovery experience in the BioPharma industry or similar.
  • Be able to evidence managing successful drug discovery projects and people.
  • Demonstrable expertise in the concepts and practice of aspects of drug discovery
  • Strong interpersonal, communication and presentation skills
  • Demonstrate initiative, with good time management, organizational and communication skills.
  • Strong interpersonal, communication and presentation skills
  • An ability to work flexibly and to meet project milestones

The post is available immediately. Salary will depend on experience but will be in the range £41,526 – £49,553

For further information about this position please contact Professor Ian Gilbert at i.h.gilbert@dundee.ac.uk.

The Biological Chemistry and Drug Discovery Division and Drug Discovery Unit operate on an external funding basis. The Principal Investigators within these units are highly successful in securing external funding for their multi-disciplinary and highly collaborative research and activities.

Working Environment

The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 1000 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.

The Drug Discovery Unit is a globally acknowledged centre of excellence for drug discovery. The DDU collaborates with partners to translate world-class biology research into novel drug targets and candidate drugs to address unmet medical need across our two areas of activity, Diseases of the Developing World and Innovative Targets Portfolio. The DDU has produced 3 clinical candidates since 2013. Over the last 3 years WCAIR has obtained multi-million pounds in grant income to found our activities and published over 85 papers, many in top ranking journals. There is a very interactive and open culture amongst WCAIR’s 170 scientists, with many collaborations between the different groups. There are also many opportunities for sharing and exchanging ideas such as weekly seminars, pizza lunches, 6-monthly symposia and an annual retreat.

The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.
Read more about why Dundee is a great place to work and live.