Medicinal Chemistry Team Leader

Reference Number SLSC0793

Grade Grade 8 (£41,526 – £49,553)

Closing Date 14 November 2020

We are seeking a highly motivated and experienced medicinal chemist with experience in the BioPharma industry or similar, for a team leader role within the Drug Discovery Unit (DDU). The successful applicant will join a dynamic and multidisciplinary group that covers all aspects of drug discovery up to candidate selection. Work will cover all aspects of early drug discovery from hit validation through to lead optimisation. The appointee will plan and lead multidisciplinary projects, line manage and co-ordinate the work of a team of chemists and drive interactions between medicinal chemists, biologists, computational chemists and drug metabolism & pharmacokinetics experts within the DDU team.

The Drug Discovery Unit  is a globally acknowledged centre of excellence for drug discovery. The DDU collaborates with partners to translate world-class biology research into novel drug targets and candidate drugs to address unmet medical need across our two areas of activity, Diseases of the Developing World and Innovative Targets Portfolio.

The post is available for an immediate start, and is funded until 31 October 2021 in the first instance. Salary will be dependent upon experience, but will be between £41,526 and £49,553

Your priorities will include

  • Work within interdisciplinary teams and actively contribute to drug discovery projects at all stages.
  • Day-to-day responsibility of delivering the project goals.
  • Lead hit validation to lead optimisation medicinal chemistry projects, to identify leads demonstrating appropriate pharmaceutical properties and efficacy in disease models.
  • Lead and mentor a team of medicinal chemists.
  • Analyse assay and pharmacokinetic data to design and synthesise target compounds
  • Write reports, presentations and publications.
  • Oversee outsourced chemistry.

Who we’re looking for

  • Candidates must be professionally qualified with a PhD in a chemical science related discipline or alternatively a BSc in a chemistry related subject with subsequent substantial relevant drug discovery experience in the BioPharma industry.
  • Be able to evidence managing successful drug discovery projects and people.
  • Demonstrable expertise in the concepts and practice of aspects of drug discovery.
  • Strong interpersonal, communication and presentation skills.
  • Demonstrate initiative, with good time management, organisational and communication skills.
  • An ability to work flexibly and to meet project milestones.

For further details regarding this exciting opportunity, please contact Professor Ian Gilbert (

The Biological Chemistry and Drug Discovery Division and Drug Discovery Unit operate on an external funding basis. The Principal Investigators within these units are highly successful in securing external funding for their multi-disciplinary and highly collaborative research and activities.